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Meta-Analysis Reveals: Low Carb Diets Promote Better Metabolic Risk Factors

Ok, another article that’s behind a paywall, and it’s just a meta analysis, but still, it’s more evidence that the tide is turning in the medical, health and nutrition community. According to the abstract of a meta-analysis just published in the American Journal of Epidemiology,

persons on low-carbohydrate diets experienced a slightly but statistically significantly lower reduction in total cholesterol (2.7 mg/dL; 95% confidence interval: 0.8, 4.6), and low density lipoprotein cholesterol (3.7 mg/dL; 95% confidence interval: 1.0, 6.4), but a greater increase in high density lipoprotein cholesterol (3.3 mg/dL; 95% confidence interval: 1.9, 4.7) and a greater decrease in triglycerides (-14.0 mg/dL; 95% confidence interval: -19.4, -8.7).

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Diet and Exercise Study Curtailed: Shows No Help For Heart Attack and Stroke for Type 2’s

Seems like our presumption that a calorie-reduction diet and an exercise regimen is the cure for all that ails us hit another snag recently. From the New York Times:

A large federal study of whether diet and weight loss can prevent heart attacks and strokes in overweight and obese people with Type 2 diabetes has ended two years ahead of schedule because the intensive program did not help.

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Mediterranean, Low Carb and Low Fat Diets: A Six Year Review

In a letter published in the New England Journal of Medicine today, researchers updated us on the results of the famed Dietary Intervention Randomized Controlled Trial (DIRECT) study (link in references below). If you don’t remember, the DIRECT study tested a low carb, low fat, and Mediterranean diet over 2 years.  At the two year mark, these were the results for weight loss:

  • −2.9±4.2 kg for the low-fat group
  • −4.4±6.0 kg for the Mediterranean-diet group
  • −4.7±6.5 kg for the low-carbohydrate group

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It Turns Out Low Carb Ketogenic Diets Are Beneficial for Type 2 Diabetics

I’ve seen a few mentions of some new research coming out in the October issue of Nutrition regarding the beneficial effects of low carb and very low carb ketogenic diets for the treatment of type 2 diabetics. Unfortunately, the main article is behind a paywall, but the abstract looks tantalizing:

  • Experiment duration was 24 weeks. Much research is flawed because the duration is absurdly short…this appears to be of sufficient duration to begin to offer meaningful results.
  • 102 diagnosed type 2 diabetics were tested among ~300 subjects
  • Body weight, body mass index, changes in waist circumference, blood glucose level, changes in hemoglobin and glycosylated hemoglobin, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, uric acid, urea and creatinine were measured every 4 weeks

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