Let’s start with a few givens (i.e. things that are well documented and known):
Cortisol is the “stress” hormone. It is good in small amounts (getting you up in the morning, running away from lions) and bad in the chronic long term (immune suppression, abdominal “beer belly” obesity).
Serotonin is the regulator of the six F’s: Fight, Flight, Food, Falling asleep, Feeling good, and… Sex. Too much is bad too little is bad. The same story as cortisol.
Serotonin is involved in regulating cortisol secretion by the 5-HT(2a/2c) receptors (more serotonin, less cortisol)
In an earlier post, we wrote that today’s biochemistry defines disease as failure to heal. This biochemistry further shows that failure to heal is caused by the modern American diet. What is wrong with this diet? Too much sugar, starch, and vegetable fats and oils, and not enough protein, and fats and oils derived from animals and fish. More »
There’s a certain endearing quality to Dr. Rothman that I can’t quite put my finger on. I don’t agree with everything he says (I found myself responding instead of listening to some of his Fish Oil discussion…so I need to go back to that), but the premis of his talk seems right on target:
Our food choices are responsible for many/most of our chronic diseases
The medical establishment mostly treats the symptoms of these diseases without trying to resolve the cause of them
Sugar, vegetable oils, and refined carbohydrates should be considered toxic and removed from diet
Cholesterol is not the hobgoblin of ill health it has been made out to be
Be weary of statins (and take CoQ10 if you’re on them)
Not a huge post here…I just wanted to follow up after Karin’s fantastic look at physological insulin resistance, and some questions about my experience in the comments, I figured I’d just follow up with my blood glucose readings… (since Karin referred to them).
This is after 19 months on a low carb, ketogenic diet…
A major function of a healthy body is to continuously heal itself against almost every type of insult. Damage occurs constantly from microorganisms, cosmic rays, etc, and the body works constantly to heal itself. From my side of the world, disease is defined as failure to heal. Failure to heal in a skin wound results in a backup type of healing called scar tissue. Failure to heal in the brain causes scar tissue in the brain that experts can see during autopsy. This tissue is said to be the cause of Alzheimer’s disease. More »
Ketone Bodies and Ketosis: Ketones are organic chemicals in which an interior carbon in a molecule forms a double bond with an oxygen molecule. Acetone, a familiar chemical, is the smallest ketone possible. It is composed of three carbons, with the double bond to oxygen on the middle carbon. Biological ketone bodies include acetone, larger ketones, and biochemicals that can become ketones. The most important of the ketone bodies are hydroxybutyrate and acetoacetate, both of which are formed from condensation of two acetyl CoA molecules. Acetone is formed from a nonenzymatic decarboxylation of acetoacetate. More »
A while ago Michael and I were discussing future article topics. There are truly a plethora of avenues to go down in this area of research and there is no lack of things to research and comment on. But even though I have a couple of pretty cool MCT articles sitting around on my desk, I want an interesting topic. I want something new. Something challenging. Besides, everyone is drinking the MCT koolaid these days. It’s become passe. (Also, it upsets my stomach and I have a personal vendetta against it. So there.) More »
I put the data through a stress test and found some inconsistencies. It turns out that there was too much variance in the data to use a standardization method. As such, I completely revamped my approach and divided the nutrient data by the RDA in order to make the values unitless and bring them within similar orders of magnitude. I’m now working on getting the data published and cannot share the spreadsheet until this is done. More »
I’ve been a big fan of Mathieu Lalonde ever since I saw his Science of Nutrition lecture. Seriously, if you can buy a copy or attend one of these all day affairs, you’re going to come out with a lot of knowledge you didn’t have when you walked in.
So it was with great anticipation that I’ve been awaiting his Ancestral Health Symposium (AHS) 2012 presentation: Nutrient Density: Sticking to the Essentials. Well, it’s finally out, and as with most things Matt Lalonde, it’s well worth watching. More »