It all began in 1984 when the prestigious Noble Prize in Medicine was awarded for the revelation that the lowly drug Aspirin prevented the COX-2 enzyme from converting the biochemical arachidonic acid to pain-producing inflammatory end products.
Alzheimer’s disease is a very large, extremely costly, growing epidemic that affects older individuals. The average per-person Medicaid spending for seniors with Alzheimer disease and other dementias is 19 times higher than the average per-person Medicaid spending for all other seniors. If no changes are made, Alzheimer’s disease will cost an estimated $1.2 trillion (in today’s dollars) in 2050. Costs to Medicare and Medicaid will increase nearly 500 percent.
How can aspirin help to cure cancer?(1) This question is a consequence of long out-dated dogma of the medical establishment. The truth that puts a lie to this worn-out dogma has been available in the public domain for more than ten years.(2) The truth has been ignored, inadvertently or deliberately, by the medical establishment and by nutrition academia, which is medicine’s principal authority for nutritional ignorance and pseudoscience.
Herein you will find an account of two truths of optimum human nutrition that are slowly emerging from a huge mix of nutrition literature that clouds rather than clarifies a fundamental field of study. These two truths, also known as natural laws, evolved in the Beginning together with prehistoric Man. Through this bond between diet and Man was forged the dietary pattern that established Man’s basic requirementsh for optimum health. These tales of truth have been passed on to us through contacts from sundry sources.
In the course of research into the biochemistry and physiology of the endpoints of essential fatty acid metabolism known as eicosanoids, the mechanism by which aspirin exerts its analgesic effect was revealed. It is now known that aspirin does not prevent the COX enzyme from converting arachidonic acid to pain-producing proinflammatory eicosanoids as had long been assumed, but rather it modifies the COX enzyme by acetylating it thereby making it convert arachidonic acid to antiinflammatory eicosanoids. During these same research activities, hitherto unknown classes of naturally occurring, anti-inflammatory, pro-healing eicosanoids known as lipoxins, resolvins, protectins, neuroprotectins, and maresins were discovered. Aspirin was found to multiply many times the healing power of these natural lipid mediators by creating aspirin-triggered counterparts to all.
I checked my email the other day and found quite a surprise: Frank and Alice Ottoboni had forwarded me the following section from their upcoming 2nd edition of Modern Nutritional Diseases. They felt that the information was important enough to release right away, and invited me to publish it here as I saw fit.