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Research Finds Link Between Fructose and Pancreatic Cancer

Ashton Kutcher has been in the news a lot recently. Normally this is something well worth ignoring, but in this instance it’s interesting: He’s been promoting the new Steve Jobs movie (in which he plays Steve Jobs) by explaining how he was hospitalized after following Steve Jobs’ diet for some time. Steve Jobs apparently ate nothing but fruit.

So what happened to poor Ashton? Well, the details are quite thin: “I was doubled over in pain […] my pancreas levels were completely out of wack.” Media reports that he spent time in the hospital. The exact nature of his affliction and the treatment for it remain undisclosed.
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A Quick Note About Cancer As Metabolic Disease

Image of the cover of the book, Cancer As A Metabolic Disease, by Thomas Seyfried
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Just wanted to drop a quick note here to publicly thank Wiley for sending me a review copy of Seyfried’s book, Cancer As Metabolic Disease. It showed up on my doorstep quite unexpectedly, and of course has prompted a complete revision of my reading schedule.

I’ve only had time to thumb through it so far and, well, it’s gorgeous. Quality paper, some full color illustrations, nice binding…they certainly didn’t go cheap on this book.

So thanks again to Wiley for being so generous. I can’t wait to dig in!

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Cancer As A Metabolic Disease – Thomas Seyfried

Image of the cover of the book, Cancer As A Metabolic Disease, by Thomas Seyfried
Cancer As A Metabolic Disease, by Thomas N. Seyfried
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Some people lust after cars, or wealth, or beautiful things. Apparently, I’m demented enough to lust after books.

But what a book…

I’ve been following Seyfried for quite a while now. His talk at Ancestral Health Symposium 2013 (AHS13) is renowned. His research, promising. And his interviews, fascinating.

Cancer As A Metabolic Disease is Seyfried’s treatise on the subject, his omnibus on the subject. In it, he builds upon the concepts first articulated by Otto Warburg (of, “The Warburg Effect” fame) and covers insights gleaned from decades of research in his own lab at Boston College.
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Why We All Don’t Get Cancer – Memorial Sloan-Kettering Cancer Center

A fantastic talk at Memorial Sloan Kettering Cancer Center by Craig P. Thompson, President and CEO of Memorial Sloan Kettering.

It starts off with a great overview of cancer in general and the associated metabolic pathways of cancer cells, including the Warburg effect and why cancer cells light up in a PET scan (hint, it’s the glucose!). He also touches on the problems of overconsumption leading to increased IGF-1 stimulation and the resultant increase in glucose uptake by all cells. This, of course, drives tumogenesis.
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Targeting Energy Metabolism in Brain Cancer – Thomas Seyfried (AHS12)

Thomas Seyfried’s talk at Ancestral Health Symposium 2012 (AHS12) is a deep dive into the origins of cancer, loosely framed around the question, “Is cancer a metabolic disease?” In some ways an extremely provocative talk, but fascinating to watch him step through the science behind assertions like, “Regardless of what you might read, mutations are not the cause of cancer.” (Hint: it’s the mitochondria! “We never find completely normal mitochondria in any cancer cells.”)
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The Role of a Low Carb Ketogenic Diet in the Treatment and Prevention of Cancer – Dr. Rainer J. Klement (AHS12)

A fantastic lecture by Dr. Rainer J. Klement (Medical Physicist) of Lets Go Paleo on the role of a low carb ketogenic diet in the prevention and treatment of cancer. The actual title of the Ancestral Health Symposium 2012 (AHS12) presentation is, “Is there a role for a paleolithic lifestyle in the treatment and prevention of cancer?”, but most of the talk focuses on how a low carb diet implemented with good food quality choices (as are often found in paleo nutrition) can not only prevent cancer, but can be used as part of treatment.
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