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Metabolic Energy Control

The metabolic energy control system of the human organism is designed to be fueled by either glucose (carbohydrates) or fatty acids (lipids).1, pp. 160  In a healthy individual, the fuel of choice is largely determined by diet composition and intake schedule.  Because food intake is a batch process for most people, the availability of food in the digestive system cycles daily through full, empty, full, and so forth.  Thus, for a diet in which the macronutrients (carbohydrates, proteins, and lipids) are consistent and in reasonable proportion, it is customary for the choice of fuel to switch back and forth seamlessly between glucose and fatty acids during the day in response to the alimentation cycles.
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Research: Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways

We’ve been providing a fair bit of coverage on cancer recently, and today will be no exception.

Unfortunately, right now I can offer little more than a pointer to the research article (published in The Journal of Clinical Investigation). I’m still working my way through it and may not have the time to return. So if you’re interested in sharing your thoughts on it, please add to the comments below!
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A Biochemical Outline of a Cure for Cancer

The term “aerobic glycolysis” is confusing to biochemists because it is inherently contradictory. Aerobic refers to reactions that require oxygen, and anaerobic refers to reactions that take place without the need for oxygen. Glycolysis is a biochemical pathway that does not need or use oxygen, therefore it is anaerobic. The definitions of aerobic and anaerobic shed no light on why glycolysis is described as aerobic.
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Full Fat Goes Mainstream?

NPR’s Morning Edition aired a delightful segment on full fait dairy foods and the (to some) unexpected consequence: “people who eat higher fat dairy tend to be leaner than people who eat skim (low fat) products.” It turns out that this “high fat paradox” is present in children as well.

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Ketopia’s New Design

In January of 2012 I started Ketopia with a stock theme, an image across the top that spoke of my journey, and the intention to push the Content First philosophy to the extreme. A couple years and a few hundred posts later (by multiple contributors!), we have a true community, a unique visual identity and a new design for the website.
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Fight Cancer With A Ketogenic Diet – Ellen Davis

Image of the cover of the book, "Fight Cancer With A Ketogenic Diet"
Browse on author’s website
A very welcome stroke of luck brought us a copy of the eBook Fight Cancer with a Ketogenic Diet, 2nd Edition by Ellen Davis. It was a joy to read because of its timeliness, accuracy, and its clarity. It is written in a clear and straightforward fashion that could only come from the pen of a scholar proficient in nutritional science.

You will find Ms. Davis’ book far more instructive than the 5-star-only-diet-book-you-will-ever-need volumes on amazon.com or the well-touted, best selling diet books in book stores. Ms. Davis’ book is available on an informative website dedicated to helping people regain health through ketogenesis (www.ketogenic-diet-resource.com).
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Red Meat and Miss Information

Red meat has long been an anathema to the nutrition establishment. Not being privy to the thinking of the originators of the so-called heart-healthy diet, we assumed it was because of the association of meat with its burden of saturated fat and cholesterol, two food components condemned as promoters of heart disease.
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Prevention of Breast, Prostate, and Colorectal Cancers

Recent biochemical research into the metabolism of the essential fatty acids seems to have uncovered a major underlying cause of breast, prostate, and colorectal cancers. This biochemistry tells us that this cause is the modern American diet and that simple dietary change is capable of preventing these cancers.

Finding the cause of a disease and then removing that cause is called primary disease prevention; the disease never occurs and wellness is continuously maintained. In recent years, this definition has been changed to mean preventive medical care, namely early diagnosis and treatment. This new type of prevention utilizes regular medical checkups aimed at early diagnosis. Thus, when a disease reaches the point where it can be diagnosed, the disease is managed by regular doctor visits, prescription drugs, and surgery. This is not primary prevention.
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